Insulin resistance increases the risk of depression, even in the absence of diabetes, according to a new study.


Insulin resistance increases the risk of depression, even in the absence of diabetes, according to a new study.

Even if you don’t have full-blown diabetes, insulin resistance can make you more than twice as likely to develop serious depression, according to a recent study.

According to the findings, those who were initially healthy but later developed prediabetes were 2.6 times more likely to suffer serious depression during a nine-year period.

“Insulin-resistant people had two to three times the prevalence of depression,” said lead researcher Kathleen Watson, a Stanford University postdoctoral scholar.

Previous research has linked insulin resistance to depression, but this is the first to prove that patients who develop insulin resistance are more likely to get depression later, according to Watson.

It’s bad news for a large group of Americans who are at risk of diabetes.

According to the US Centers for Disease Control and Prevention, about one-third of all adults in the United States — more than 88 million people – have prediabetes, a condition in which insulin resistance and blood sugar levels are rising but there is still time to prevent type 2 diabetes.

Watson and her colleagues evaluated data from over 600 people in a long-term Netherlands research of depression and anxiety for the study, which was published Thursday in the American Journal of Psychiatry. The participants, who were on average 41 years old, had never felt depressed or anxious before enrolling in the study.

Researchers were able to track three indicators of insulin resistance through regular physical exams: fasting blood sugar levels, waist circumference, and the ratio of triglycerides to “good” HDL cholesterol. The individuals were also subjected to psychiatric assessments on a regular basis.

Insulin, a hormone generated by the pancreas, is used by the human body to convert blood sugar into energy. Your cells may become less able to use insulin to convert sugar to energy if your blood sugar levels remain high. Insulin resistance is what this is.

The body eventually reaches a tipping point where insulin resistance is so severe that it loses its capacity to control blood sugar levels without medication. A person is diagnosed with type 2 diabetes at this point.

Researchers discovered that as individuals in this trial became more insulin resistance over time, they became more at risk for depression:

Observing how this changes over time is “considered a stronger metric than simply assessing a group of persons with insulin resistance and seeing how they… Article Summary from Nokia News


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